Al Burlingame is Professor of Chemistry and Pharmaceutical Chemistry at UCSF. He is director of the NIH NIGMS national Center for Mass Spectrometry and Proteomics and is co-Editor of Molecular and Cellular Proteomics. His research interests focus on development of new microanalytical methodologies, mass spectrometric strategies and software tools to address challenging problems in protein biology. His current work is focused on the detection, assignment and dynamics of posttranslational modifications of proteins, particularily O-GlcNAcylation, phosphorylation, proteolytic processing, acetylation, methylation and ubiquitinylation. In addition, considerable effort concerns studies of the architecture of protein complexes and machines.
Title of the talk:
"Studies using electron transfer dissociation(ETD) MS have accelerated the assignment O-GlcNAc protein site occupancies and the discovery of their diverse roles in biological function"